Extragenic suppressor mutations that restore twitching motility to fimL mutants of Pseudomonas aeruginosa are associated with elevated intracellular cyclic AMP levels

Cyclic AMP (cAMP) is a signaling molecule that is involved in the regulation of multiple virulence systems of the opportunistic pathogen Pseudomonas aeruginosa. The intracellular concentration of cAMP in P. aeruginosa cells is tightly controlled at the levels of cAMP synthesis and degradation throug...

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Hlavní autoři: Nolan, Laura M, Beatson, Scott A, Croft, Larry, Jones, Peter M, George, Anthony M, Mattick, John S, Turnbull, Lynne, Whitchurch, Cynthia B
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535393/
https://ncbi.nlm.nih.gov/pubmed/23233287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.49
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