Extragenic suppressor mutations that restore twitching motility to fimL mutants of Pseudomonas aeruginosa are associated with elevated intracellular cyclic AMP levels

Cyclic AMP (cAMP) is a signaling molecule that is involved in the regulation of multiple virulence systems of the opportunistic pathogen Pseudomonas aeruginosa. The intracellular concentration of cAMP in P. aeruginosa cells is tightly controlled at the levels of cAMP synthesis and degradation throug...

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Bibliographic Details
Main Authors: Nolan, Laura M, Beatson, Scott A, Croft, Larry, Jones, Peter M, George, Anthony M, Mattick, John S, Turnbull, Lynne, Whitchurch, Cynthia B
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535393/
https://ncbi.nlm.nih.gov/pubmed/23233287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.49
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