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Multi-cell type human liver microtissues for hepatotoxicity testing
Current 2-dimensional hepatic model systems often fail to predict chemically induced hepatotoxicity due to the loss of a hepatocyte-specific phenotype in culture. For more predictive in vitro models, hepatocytes have to be maintained in a 3-dimensional environment that allows for polarization and ce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535351/ https://ncbi.nlm.nih.gov/pubmed/23143619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-012-0968-2 |
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