Interactions of Everolimus and Sorafenib in Pancreatic Cancer Cells

Everolimus targets the mammalian target of rapamycin, a kinase that promotes cell growth and proliferation in pancreatic cancer. Sorafenib inhibits the Raf-mitogen-activated protein kinase, vascular endothelial growth factor, and platelet-derived growth factor pathways, thus inhibiting cell growth a...

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Detalles Bibliográficos
Autores principales: Pawaskar, Dipti K., Straubinger, Robert M., Fetterly, Gerald J., Ma, Wen W., Jusko, William J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535103/
https://ncbi.nlm.nih.gov/pubmed/23054975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9417-7
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