Vorinostat, an HDAC Inhibitor Attenuates Epidermoid Squamous Cell Carcinoma Growth by Dampening mTOR Signaling Pathway in a Human Xenograft Murine Model

Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and has shown potential to inhibit growth of human xenograft tumors. However, its effect on the growth of skin neoplasm remains undefined. In th...

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Autores principales: Kurundkar, Deepali, Srivastava, Ritesh K., Chaudhary, Sandeep C., Ballestas, Mary E., Kopelovich, Levy, Elmets, Craig A., Athar, Mohammad
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534787/
https://ncbi.nlm.nih.gov/pubmed/23147569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.11.002
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