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The role of saposin C in Gaucher disease

Saposin C is one of four homologous proteins derived from sequential cleavage of the saposin precursor protein, prosaposin. It is an essential activator for glucocerebrosidase, the enzyme deficient in Gaucher disease. Gaucher disease is a rare autosomal recessive lysosomal storage disorder caused by...

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Bibliografische gegevens
Hoofdauteurs: Tamargo, Rafael J., Velayati, Arash, Goldin, Ehud, Sidransky, Ellen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534739/
https://ncbi.nlm.nih.gov/pubmed/22652185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.04.024
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