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Oculus: faster sequence alignment by streaming read compression

BACKGROUND: Despite significant advancement in alignment algorithms, the exponential growth of nucleotide sequencing throughput threatens to outpace bioinformatic analysis. Computation may become the bottleneck of genome analysis if growing alignment costs are not mitigated by further improvement in...

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Bibliografiske detaljer
Main Authors: Veeneman, Brendan A, Iyer, Matthew K, Chinnaiyan, Arul M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534618/
https://ncbi.nlm.nih.gov/pubmed/23148484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-297
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