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Oculus: faster sequence alignment by streaming read compression

BACKGROUND: Despite significant advancement in alignment algorithms, the exponential growth of nucleotide sequencing throughput threatens to outpace bioinformatic analysis. Computation may become the bottleneck of genome analysis if growing alignment costs are not mitigated by further improvement in...

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Detalhes bibliográficos
Main Authors: Veeneman, Brendan A, Iyer, Matthew K, Chinnaiyan, Arul M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534618/
https://ncbi.nlm.nih.gov/pubmed/23148484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-297
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