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Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction
BACKGROUND: Previous studies have noted that drug targets appear to be associated with higher-degree or higher-centrality proteins in interaction networks. These studies explicitly or tacitly make choices of different source databases, data integration strategies, representation of proteins and comp...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534413/ https://ncbi.nlm.nih.gov/pubmed/23146171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-294 |
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