Airway CD8(+) T cells induced by pulmonary DNA immunization mediate protective anti-viral immunity

Vaccination strategies for protection against a number of respiratory pathogens must induce T-cell populations in both the pulmonary airways and peripheral lymphoid organs. In this study, we show that pulmonary immunization using plasmid DNA formulated with the polymer polyethyleneimine (PEI-DNA) in...

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Main Authors: Bivas-Benita, M, Gillard, G O, Bar, L, White, K A, Webby, R J, Hovav, A-H, Letvin, N L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534169/
https://ncbi.nlm.nih.gov/pubmed/22806099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.59
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