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Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: Electron microscopy, tomography and oxygen consumption

PURPOSE: Postnatal lead exposure produces rod-selective and Bax-mediated apoptosis, decreased scotopic electroretinograms (ERGs), and scotopic and mesopic vision deficits in humans and/or experimental animals. Rod, but not cone, inner segment mitochondria were considered the primary site of action....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Perkins, Guy A., Scott, Ray, Perez, Alex, Ellisman, Mark H., Johnson, Jerry E., Fox, Donald A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Vision 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534145/
https://ncbi.nlm.nih.gov/pubmed/23288995
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