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Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: Electron microscopy, tomography and oxygen consumption

PURPOSE: Postnatal lead exposure produces rod-selective and Bax-mediated apoptosis, decreased scotopic electroretinograms (ERGs), and scotopic and mesopic vision deficits in humans and/or experimental animals. Rod, but not cone, inner segment mitochondria were considered the primary site of action....

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Detalhes bibliográficos
Main Authors: Perkins, Guy A., Scott, Ray, Perez, Alex, Ellisman, Mark H., Johnson, Jerry E., Fox, Donald A.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534145/
https://ncbi.nlm.nih.gov/pubmed/23288995
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