Pigment Epithelium-Derived Factor (PEDF) Peptide Eye Drops Reduce Inflammation, Cell Death and Vascular Leakage in Diabetic Retinopathy in Ins2(Akita) Mice

Inflammation, neurodegeneration and microvascular irregularities are included in the spectrum of defects associated with diabetic retinopathy. Here, we evaluated intraocular deliverability features of two pigment epithelium-derived factor (PEDF) derivatives given as eye drops and their efficacy in m...

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Bibliographic Details
Main Authors: Liu, Yanling, Leo, Lan Franco, McGregor, Corban, Grivitishvili, Anzor, Barnstable, Colin J, Tombran-Tink, Joyce
Format: Artigo
Language:Inglês
Published: ScholarOne 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533643/
https://ncbi.nlm.nih.gov/pubmed/23019073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00008
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