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Pigment Epithelium-Derived Factor (PEDF) Peptide Eye Drops Reduce Inflammation, Cell Death and Vascular Leakage in Diabetic Retinopathy in Ins2(Akita) Mice

Inflammation, neurodegeneration and microvascular irregularities are included in the spectrum of defects associated with diabetic retinopathy. Here, we evaluated intraocular deliverability features of two pigment epithelium-derived factor (PEDF) derivatives given as eye drops and their efficacy in m...

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Bibliografiske detaljer
Main Authors: Liu, Yanling, Leo, Lan Franco, McGregor, Corban, Grivitishvili, Anzor, Barnstable, Colin J, Tombran-Tink, Joyce
Format: Artigo
Sprog:Inglês
Udgivet: ScholarOne 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533643/
https://ncbi.nlm.nih.gov/pubmed/23019073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00008
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