Loading...
Codon Preference Optimization Increases Heterologous PEDF Expression
Pigment epithelium-derived factor (PEDF) is widely known for its neurotrophic and antiangiogenic functions. Efficacy studies of PEDF in animal models are limited because of poor heterologous protein yields. Here, we redesigned the human PEDF gene to preferentially match codon frequencies of E coli w...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2010
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994832/ https://ncbi.nlm.nih.gov/pubmed/21152082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015056 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|