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Molecular phylogeny of the antiangiogenic and neurotrophic serpin, pigment epithelium derived factor in vertebrates

BACKGROUND: Pigment epithelium derived factor (PEDF), a member of the serpin family, regulates cell proliferation, promotes survival of neurons, and blocks growth of new blood vessels in mammals. Defining the molecular phylogeny of PEDF by bioinformatic analysis is one approach to understanding the...

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Detalhes bibliográficos
Main Authors: Xu, Xuming, Zhang, Samuel Shao-Min, Barnstable, Colin J, Tombran-Tink, Joyce
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1609119/
https://ncbi.nlm.nih.gov/pubmed/17020603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-248
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