Pathway-specific dopaminergic deficits in a mouse model of Angelman syndrome

Angelman syndrome (AS) is a neurodevelopmental disorder caused by maternal deletions or mutations of the ubiquitin ligase E3A (UBE3A) allele and characterized by minimal verbal communication, seizures, and disorders of voluntary movement. Previous studies have suggested that abnormal dopamine neurot...

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Detalhes bibliográficos
Main Authors: Riday, Thorfinn T., Dankoski, Elyse C., Krouse, Michael C., Fish, Eric W., Walsh, Paul L., Han, Ji Eun, Hodge, Clyde W., Wightman, R. Mark, Philpot, Benjamin D., Malanga, C.J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533533/
https://ncbi.nlm.nih.gov/pubmed/23143301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61888
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