Isolation, Amino Acid Sequence and Biological Activities of Novel Long-Chain Polyamine-Associated Peptide Toxins from the Sponge Axinyssa aculeata

A novel family of functionalized peptide toxins, aculeines (ACUs), was isolated from the marine sponge Axinyssa aculeate. ACUs are polypeptides with N-terminal residues that are modified by the addition of long-chain polyamines (LCPA). Aculeines were present in the sponge extract as a complex mixtur...

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Hauptverfasser: Matsunaga, Satoko, Jimbo, Mitsuru, Gill, Martin B., Lash-Van Wyhe, L. Leanne, Murata, Michio, Nonomura, Ken’ichi, Swanson, Geoffrey T., Sakai, Ryuichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533443/
https://ncbi.nlm.nih.gov/pubmed/21830292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100329
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