p53 Functions in Endothelial Cells to Prevent Radiation-Induced Myocardial Injury in Mice

p53 functions in the heart to promote myocardial injury after multiple types of stress. However, how p53 regulates radiation-induced myocardial injury, which develops after radiation therapy, is not well understood. Here, we utilize the Cre-loxP system to demonstrate that p53 functioned in endotheli...

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Detalhes bibliográficos
Main Authors: Lee, Chang-Lung, Moding, Everett J., Cuneo, Kyle C., Li, Yifan, Sullivan, Julie M., Mao, Lan, Washington, Iman, Jeffords, Laura B., Rodrigues, Rafaela C., Ma, Yan, Das, Shiva, Kontos, Christopher D., Kim, Yongbaek, Rockman, Howard A., Kirsch, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533440/
https://ncbi.nlm.nih.gov/pubmed/22827996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002918
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