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Lithium rescues synaptic plasticity and memory in Down syndrome mice
Down syndrome (DS) patients exhibit abnormalities of hippocampal-dependent explicit memory, a feature that is replicated in relevant mouse models of the disease. Adult hippocampal neurogenesis, which is impaired in DS and other neuropsychiatric diseases, plays a key role in hippocampal circuit plast...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533293/ https://ncbi.nlm.nih.gov/pubmed/23202733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64650 |
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