Lithium rescues synaptic plasticity and memory in Down syndrome mice

Down syndrome (DS) patients exhibit abnormalities of hippocampal-dependent explicit memory, a feature that is replicated in relevant mouse models of the disease. Adult hippocampal neurogenesis, which is impaired in DS and other neuropsychiatric diseases, plays a key role in hippocampal circuit plast...

Full description

Saved in:
Bibliographic Details
Main Authors: Contestabile, Andrea, Greco, Barbara, Ghezzi, Diego, Tucci, Valter, Benfenati, Fabio, Gasparini, Laura
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533293/
https://ncbi.nlm.nih.gov/pubmed/23202733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64650
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items