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Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs
TLR activation on CD11c(+) DCs triggers DC maturation, which is critical for T cell activation. Given the expansion of CD11c(+) DCs during the progression of atherosclerosis and the key role of T cell activation in atherogenesis, we sought to understand the role of TLR signaling in CD11c(+) DCs in a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533292/ https://ncbi.nlm.nih.gov/pubmed/23257360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64617 |
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