MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma

MicroRNAs (miRNAs) and methionine adenosyltransferase 1A (MAT1A) are dysregulated in hepatocellular carcinoma (HCC), and reduced MAT1A expression correlates with worse HCC prognosis. Expression of miR-664, miR-485-3p, and miR-495, potential regulatory miRNAs of MAT1A, is increased in HCC. Knockdown...

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Autori principali: Yang, Heping, Cho, Michele E., Li, Tony W.H., Peng, Hui, Ko, Kwang Suk, Mato, Jose M., Lu, Shelly C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533284/
https://ncbi.nlm.nih.gov/pubmed/23241961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63861
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