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Synthesis and characterization of a small analogue of the anticancer natural product leinamycin
Leinamycin (1) is a Streptomyces-derived natural product that displays nanomolar IC(50) values against human cancer cell lines. In the work described here, we report the synthesis and characterization of a small leinamycin analogue 19 that closely resembles the “upper-right quadrant” of the natural...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532941/ https://ncbi.nlm.nih.gov/pubmed/23168080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.10.021 |
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