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A High-Throughput Screening Assay for the Identification of Flavivirus NS5 Capping Enzyme GTP-Binding Inhibitors: Implications for Antiviral Drug Development

There are no effective antivirals currently available for the treatment of flavivirus infection in humans. As such, the identification and characterization of novel drug target sites are critical to developing new classes of antiviral drugs. The flavivirus NS5 N-terminal capping enzyme (CE) is vital...

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Autors principals: GEISS, BRIAN J., STAHLA-BEEK, HILLARY J., HANNAH, AMANDA M., GARI, HAMID H., HENDERSON, BRITTNEY R., SAEEDI, BEJAN J., KEENAN, SUSAN M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532936/
https://ncbi.nlm.nih.gov/pubmed/21788392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057111412183
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