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Identification of a Novel Antiviral Inhibitor of the Flavivirus Guanylyltransferase Enzyme

Arthropod-borne flavivirus infection causes serious morbidity and mortality worldwide, but there are currently no effective antiflaviviral chemotherapeutics available for human use. Therefore, it is critical that new therapeutics against virus-specific targets be developed. To identify new compounds...

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Главные авторы: Stahla-Beek, Hillary J., April, Daniel G., Saeedi, Bejan J., Hannah, Amanda M., Keenan, Susan M., Geiss, Brian J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421717/
https://ncbi.nlm.nih.gov/pubmed/22674988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00384-12
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