Retinoic Acid Induces Apoptosis of Prostate Cancer DU145 Cells through Cdk5 Overactivation

Retinoic acid (RA) has been believed to be an anticancer drug for a long history. However, the molecular mechanisms of RA actions on cancer cells remain diverse. In this study, the dose-dependent inhibition of RA on DU145 cell proliferation was identified. Interestingly, RA treatment triggered p35 c...

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Detalhes bibliográficos
Main Authors: Chen, Mei-Chih, Huang, Chih-Yang, Hsu, Shih-Lan, Lin, Eugene, Ku, Chien-Te, Lin, Ho, Chen, Chuan-Mu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532922/
https://ncbi.nlm.nih.gov/pubmed/23304206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/580736
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