Secreted gelsolin desensitizes and induces apoptosis of infiltrated lymphocytes in prostate cancer

Loss of immunosurveillance is a major cause of cancer progression. Here, we demonstrate that gelsolin, a constituent of ejaculate, induces apoptosis of activated lymphocytes in prostate cancer. Gelsolin was highly expressed in prostate cancer cells, and was associated with tumor progression, recurre...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Chun-Chi, Chiou, Shiow-Her, Yang, Cheng-Lin, Chow, Kuan-Chih, Lin, Tze-Yi, Chang, Hui-Wen, You, Weir-Chiang, Huang, Hisu-Wen, Chen, Chien-Min, Chen, Nien-Cheng, Chou, Fen-Pi, Chou, Ming-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652770/
https://ncbi.nlm.nih.gov/pubmed/29100377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20414
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