The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) has, in recent years, emerged as an important tumor cell behavior associated with high metastatic potential and drug resistance. Interestingly, protein SUMOylation and hepatocyte growth factor could respectively reduce the effect of small molecu...

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Dettagli Bibliografici
Pubblicato in:J Hematol Oncol
Autori principali: Joseph, Nithila A., Chiou, Shiow-Her, Lung, Zoe, Yang, Cheng-Lin, Lin, Tze-Yi, Chang, Hui-Wen, Sun, H. Sunny, Gupta, Sachin Kumar, Yen, Laising, Wang, Shulhn-Der, Chow, Kuan-Chih
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984410/
https://ncbi.nlm.nih.gov/pubmed/29855336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0557-9
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