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A new direction for gene looping
Upon binding to a promoter, RNA polymerase II can synthesize either a coding mRNA or a divergently transcribed non-coding RNA. In a recent issue of Science, Tan-Wong et al. (2012) find that intragenic looping increases the proper orientation of RNA polymerase II, reducing the production of divergent...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3532906/ https://ncbi.nlm.nih.gov/pubmed/23153489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.10.024 |
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