GENE LOOPS ENHANCE TRANSCRIPTIONAL DIRECTIONALITY

Eukaryotic genomes are extensively transcribed, forming both messenger (m) and noncoding (nc) RNAs. ncRNAs made by RNA polymerase II (Pol II) often initiate from bidirectional promoters (nucleosome-depleted chromatin) that synthesise mRNA and ncRNA in opposite directions. We demonstrate that activel...

Full description

Saved in:
Bibliographic Details
Main Authors: Tan-Wong, Sue Mei, Zaugg, Judith B., Camblong, Jurgi, Xu, Zhenyu, Zhang, David W., Mischo, Hannah E., Ansari, Aseem Z., Luscombe, Nicholas M., Steinmetz, Lars M., Proudfoot, Nick J.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563069/
https://ncbi.nlm.nih.gov/pubmed/23019609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224350
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items