GENE LOOPS ENHANCE TRANSCRIPTIONAL DIRECTIONALITY

Eukaryotic genomes are extensively transcribed, forming both messenger (m) and noncoding (nc) RNAs. ncRNAs made by RNA polymerase II (Pol II) often initiate from bidirectional promoters (nucleosome-depleted chromatin) that synthesise mRNA and ncRNA in opposite directions. We demonstrate that activel...

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Bibliografische gegevens
Hoofdauteurs: Tan-Wong, Sue Mei, Zaugg, Judith B., Camblong, Jurgi, Xu, Zhenyu, Zhang, David W., Mischo, Hannah E., Ansari, Aseem Z., Luscombe, Nicholas M., Steinmetz, Lars M., Proudfoot, Nick J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563069/
https://ncbi.nlm.nih.gov/pubmed/23019609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224350
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