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GENE LOOPS ENHANCE TRANSCRIPTIONAL DIRECTIONALITY
Eukaryotic genomes are extensively transcribed, forming both messenger (m) and noncoding (nc) RNAs. ncRNAs made by RNA polymerase II (Pol II) often initiate from bidirectional promoters (nucleosome-depleted chromatin) that synthesise mRNA and ncRNA in opposite directions. We demonstrate that activel...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563069/ https://ncbi.nlm.nih.gov/pubmed/23019609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224350 |
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