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Antibody Against TcdB, but Not TcdA, Prevents Development of Gastrointestinal and Systemic Clostridium difficile Disease

Background. A dramatic increase in morbidity and mortality from Clostridium difficile infection (CDI) due to the recent emergence of virulent, antibiotic-resistant strains has led to a search for alternatives to antibiotics, including vaccines and immune-based therapy that target the 2 key toxins—Tc...

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Bibliografiske detaljer
Main Authors: Steele, Jennifer, Mukherjee, Jean, Parry, Nicola, Tzipori, Saul
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532825/
https://ncbi.nlm.nih.gov/pubmed/23125448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis669
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