Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without effective therapeutics. Periostin has been reported to be elevated in IPF patients relative to controls, but its sources and mechanisms of action remain unclear. We confirm excess periostin in lungs of IPF patients an...

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Autori principali: Naik, Payal K., Bozyk, Paul D., Bentley, J. Kelley, Popova, Antonia P., Birch, Carolyn M., Wilke, Carol A., Fry, Christopher D., White, Eric S., Sisson, Thomas H., Tayob, Nabihah, Carnemolla, Barbara, Orecchia, Paola, Flaherty, Kevin R., Hershenson, Marc B., Murray, Susan, Martinez, Fernando J., Moore, Bethany B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532583/
https://ncbi.nlm.nih.gov/pubmed/23043074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00139.2012
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