Periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis

Fibrocytes are circulating mesenchymal precursors (CD45+, col 1+) recruited to fibrotic areas. Fibrocytes secrete profibrotic mediators including periostin; a matricellular protein that regulates cellular interactions with extracellular matrix (ECM) components. In bleomycin-induced fibrosis, periost...

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Bibliographic Details
Published in:Mucosal Immunol
Main Authors: Ashley, Shanna L., Wilke, Carol A., Kim, Kevin K., Moore, Bethany B.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250615/
https://ncbi.nlm.nih.gov/pubmed/27435108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.61
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