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Histamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells

Histamine, an inflammatory mediator, has been shown to influence the pathogenesis of vascular wall cells. However, the molecular basis of its influence is not well understood. Our data reveal that histamine markedly induces protein kinase D (PKD) activation in human aortic smooth muscle cells. PKD b...

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Autors principals: Hao, Feng, Wu, Daniel Dongwei, Xu, Xuemin, Cui, Mei-Zhen
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532537/
https://ncbi.nlm.nih.gov/pubmed/23001835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00500.2011
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