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LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA(1)-regulated, PKC-dependent, and p38α-mediated pathway
Lysophosphatidic acid (LPA) is a potent bioactive lysophospholipid. Accumulated evidence supports a role for LPA in inflammation. To profile LPA-induced cytokine production in vascular smooth muscle cells (SMCs), we used a cytokine antibody array system and found that LPA prominently induces the sec...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838556/ https://ncbi.nlm.nih.gov/pubmed/20044439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00895.2009 |
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