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Regulation of the renal Na(+)-Cl(−) cotransporter by phosphorylation and ubiquitylation

The activity of the renal thiazide-sensitive NaCl cotransporter (NCC) in the distal convoluted tubule plays a key role in defining arterial blood pressure levels. Increased or decreased activity of the NCC is associated with arterial hypertension or hypotension, respectively. Thus it is of major int...

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Autore principale: Gamba, Gerardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532472/
https://ncbi.nlm.nih.gov/pubmed/23034942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00508.2012
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