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Oscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops

BACKGROUND: Feedback loops, both positive and negative are embedded in the Mitogen Activated Protein Kinase (MAPK) cascade. In the three layer MAPK cascade, both feedback loops originate from the terminal layer and their sites of action are either of the two upstream layers. Recent studies have show...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sarma, Uddipan, Ghosh, Indira
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532088/
https://ncbi.nlm.nih.gov/pubmed/22694947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-287
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