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Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops

A simple negative feedback loop of interacting genes or proteins has the potential to generate sustained oscillations. However, many biological oscillators also have a positive feedback loop, raising the question of what advantages the extra loop imparts. Through computational studies, we show that...

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Bibliografski detalji
Glavni autori: Tsai, Tony Yu-Chen, Choi, Yoon Sup, Ma, Wenzhe, Pomerening, Joseph R., Tang, Chao, Ferrell, James E.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728800/
https://ncbi.nlm.nih.gov/pubmed/18599789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1156951
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