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Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops
A simple negative feedback loop of interacting genes or proteins has the potential to generate sustained oscillations. However, many biological oscillators also have a positive feedback loop, raising the question of what advantages the extra loop imparts. Through computational studies, we show that...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728800/ https://ncbi.nlm.nih.gov/pubmed/18599789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1156951 |
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