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Oscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops

BACKGROUND: Feedback loops, both positive and negative are embedded in the Mitogen Activated Protein Kinase (MAPK) cascade. In the three layer MAPK cascade, both feedback loops originate from the terminal layer and their sites of action are either of the two upstream layers. Recent studies have show...

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Autors principals: Sarma, Uddipan, Ghosh, Indira
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532088/
https://ncbi.nlm.nih.gov/pubmed/22694947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-287
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