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NGF–promoted axon growth and target innervation requires GITRL–GITR signalling

NGF plays a pivotal role in regulating sympathetic neuron survival and target field innervation during development. Here we show that a member of the TNF superfamily, GITR and its ligand GITRL are co–expressed in mouse sympathetic neurons when their axons are innervating their targets under the infl...

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מידע ביבליוגרפי
Main Authors: O'Keeffe, Gerard W., Gutierrez, Humberto, Pandolfi, Pier Paolo, Riccardi, Carlo, Davies, Alun M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531920/
https://ncbi.nlm.nih.gov/pubmed/18176559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn2034
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