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NGF–promoted axon growth and target innervation requires GITRL–GITR signalling
NGF plays a pivotal role in regulating sympathetic neuron survival and target field innervation during development. Here we show that a member of the TNF superfamily, GITR and its ligand GITRL are co–expressed in mouse sympathetic neurons when their axons are innervating their targets under the infl...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531920/ https://ncbi.nlm.nih.gov/pubmed/18176559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn2034 |
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