BRCA1 Immunohistochemistry in a Molecularly Characterized Cohort of Ovarian Carcinomas

BRCA1 and BRCA2 dysfunction, frequently seen in high-grade serous ovarian carcinomas, often results from germline mutations, somatic mutations, and promoter methylation. Identification of tumors with BRCA defects has therapeutic and prognostic implications. Identifying germline BRCA mutations is als...

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Hlavní autoři: Garg, Karuna, Levine, Douglas A, Olvera, Narciso, Dao, Fanny, Bisogna, Maria, Secord, Angeles Alvarez, Berchuck, Andrew, Cerami, Ethan, Schultz, Nikolaus, Soslow, Robert A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531916/
https://ncbi.nlm.nih.gov/pubmed/23232854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e31826cabbd
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