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BRCA1 Immunohistochemistry in a Molecularly Characterized Cohort of Ovarian Carcinomas
BRCA1 and BRCA2 dysfunction, frequently seen in high-grade serous ovarian carcinomas, often results from germline mutations, somatic mutations, and promoter methylation. Identification of tumors with BRCA defects has therapeutic and prognostic implications. Identifying germline BRCA mutations is als...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3531916/ https://ncbi.nlm.nih.gov/pubmed/23232854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e31826cabbd |
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