Role of superoxide–nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase

Mice lacking Cu,Zn superoxide dismutase (SOD1) show accelerated, age-related loss of muscle mass. Lack of SOD1 may lead to increased superoxide, reduced nitric oxide (NO), and increased peroxynitrite, each of which could initiate muscle fiber loss. Single muscle fibers from flexor digitorum brevis o...

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Detalhes bibliográficos
Main Authors: Sakellariou, Giorgos K, Pye, Deborah, Vasilaki, Aphrodite, Zibrik, Lea, Palomero, Jesus, Kabayo, Tabitha, McArdle, Francis, Van Remmen, Holly, Richardson, Arlan, Tidball, James G, McArdle, Anne, Jackson, Malcolm J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531889/
https://ncbi.nlm.nih.gov/pubmed/21443684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00709.x
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