Lysosomal Rerouting of Hsp70 Trafficking as a Potential Immune Activating Tool for Targeting Melanoma

Tumor specific cell surface localization and release of the stress inducible heat shock protein 70 (Hsp70) stimulate the immune system against cancer cells. A key immune stimulatory function of tumor-derived Hsp70 has been exemplified with the murine melanoma cell model, B16 overexpressing exogenous...

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Main Authors: Juhász, Kata, Thuenauer, Roland, Spachinger, Andrea, Duda, Ernő, Horváth, Ibolya, Vígh, László, Sonnleitner, Alois, Balogi, Zsolt
Format: Artigo
Jezik:Inglês
Izdano: Bentham Science Publishers 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531874/
https://ncbi.nlm.nih.gov/pubmed/22920897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138161213804143644
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