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RAD51 and Breast Cancer Susceptibility: No Evidence for Rare Variant Association in the Breast Cancer Family Registry Study

BACKGROUND: Although inherited breast cancer has been associated with germline mutations in genes that are functionally involved in the DNA homologous recombination repair (HRR) pathway, including BRCA1, BRCA2, TP53, ATM, BRIP1, CHEK2 and PALB2, about 70% of breast cancer heritability remains unexpl...

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Autori principali: Le Calvez-Kelm, Florence, Oliver, Javier, Damiola, Francesca, Forey, Nathalie, Robinot, Nivonirina, Durand, Geoffroy, Voegele, Catherine, Vallée, Maxime P., Byrnes, Graham, Registry, Breast Cancer Family, Hopper, John L., Southey, Melissa C., Andrulis, Irene L., John, Esther M., Tavtigian, Sean V., Lesueur, Fabienne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531476/
https://ncbi.nlm.nih.gov/pubmed/23300655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052374
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