RAD51 and Breast Cancer Susceptibility: No Evidence for Rare Variant Association in the Breast Cancer Family Registry Study

BACKGROUND: Although inherited breast cancer has been associated with germline mutations in genes that are functionally involved in the DNA homologous recombination repair (HRR) pathway, including BRCA1, BRCA2, TP53, ATM, BRIP1, CHEK2 and PALB2, about 70% of breast cancer heritability remains unexpl...

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Bibliographic Details
Main Authors: Le Calvez-Kelm, Florence, Oliver, Javier, Damiola, Francesca, Forey, Nathalie, Robinot, Nivonirina, Durand, Geoffroy, Voegele, Catherine, Vallée, Maxime P., Byrnes, Graham, Registry, Breast Cancer Family, Hopper, John L., Southey, Melissa C., Andrulis, Irene L., John, Esther M., Tavtigian, Sean V., Lesueur, Fabienne
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531476/
https://ncbi.nlm.nih.gov/pubmed/23300655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052374
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