RAD51 and Breast Cancer Susceptibility: No Evidence for Rare Variant Association in the Breast Cancer Family Registry Study

BACKGROUND: Although inherited breast cancer has been associated with germline mutations in genes that are functionally involved in the DNA homologous recombination repair (HRR) pathway, including BRCA1, BRCA2, TP53, ATM, BRIP1, CHEK2 and PALB2, about 70% of breast cancer heritability remains unexpl...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Le Calvez-Kelm, Florence, Oliver, Javier, Damiola, Francesca, Forey, Nathalie, Robinot, Nivonirina, Durand, Geoffroy, Voegele, Catherine, Vallée, Maxime P., Byrnes, Graham, Registry, Breast Cancer Family, Hopper, John L., Southey, Melissa C., Andrulis, Irene L., John, Esther M., Tavtigian, Sean V., Lesueur, Fabienne
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531476/
https://ncbi.nlm.nih.gov/pubmed/23300655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052374
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky