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The Two Sides of Complement C3d: Evolution of Electrostatics in a Link between Innate and Adaptive Immunity

The interaction between complement fragment C3d and complement receptor 2 (CR2) is a key aspect of complement immune system activation, and is a component in a link between innate and adaptive immunities. The complement immune system is an ancient mechanism for defense, and can be found in species t...

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Bibliographic Details
Main Authors: Kieslich, Chris A., Morikis, Dimitrios
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531323/
https://ncbi.nlm.nih.gov/pubmed/23300422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002840
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