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Immunophysical Properties and Prediction of Activities for Vaccinia Virus Complement Control Protein and Smallpox Inhibitor of Complement Enzymes Using Molecular Dynamics and Electrostatics
We present immunophysical modeling for VCP, SPICE, and three mutants using MD simulations and Poisson-Boltzmann-type electrostatic calculations. VCP and SPICE are homologous viral proteins that control the complement system by imitating, structurally and functionally, natural regulators of complemen...
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| Main Authors: | , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Biophysical Society
2006
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1432100/ https://ncbi.nlm.nih.gov/pubmed/16473914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068130 |
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